Dr.S Ajikumaran Nair
Position:Technical Officer Gr. V
Research Gate link
Qualifications
Specialization
Ongoing Projects
Publications
✤ Ajikumaran Nair S , Rajani Kurup SR , Akhila S Nair ,Sabulal Baby (2018). Citrus peels prevent cancer. Phytomedicine. DOI: 10.1016/j.phymed.2017.08.011, Elsevier.IF: 7.9.
✤ Ajikumaran Nair S, Sabulal, Radhika J,.Arunkumar R, Subramoniam A (2014). Promising anti-diabetes mellitus activity in rats of β-amyrin palmitate isolated from Hemidesmus indicus roots. European Journal of Pharmacology,734:77–82. Elsevier. IF: 5.19.
✤ Ajikumaran Nair Sadasivan Nair, Reshma Vijayakumari Raveendran Nair, Aroma Prasanna Rajendran Nair, Akhila Sasikumar Nair, Sabu Thyagarajan, Anil John Johnson, Sabulal Baby (2020). Antidiabetes constituents, cycloartenol and 24-methylenecycloartanol, from Ficus krishnae. PLoS One, Jun 25;15(6):e0235221. doi: 10.1371/journal.pone.0235221. Public Library of Science, USA. IF: 3.7.
✤ Subramoniam A, Asha VV, Ajikumaran Nair S, Sreejith PS, Sureshkumar PK, Rajendran K, Karunagaran D and Ramalingam K (2011). Chlorophyll Revisited: Anti-inflammatory Activities of Chlorophyll-a and Inhibition of Expression of TNF-α Gene by the Same. Inflammation, 35: 959-66 (DOI: 10.1007/s10753-011-9399-0). Springer. IF: 5.1.
✤ Ajikumaran Nair S, Shylesh B S, Gopakumar B, Subramoniam A (2006). Anti-diabetes and hypoglycaemic properties of Hemionitis arifolia (Burm.) Moore in rats. Journal of Ethnopharmacology 106: 192-197.Elsevier. IF: 5.4.
✤ Renju Kunjumon, Gayathri Viswanathan, Sabulal Baby. (2021). Biocompatible madecassoside encapsulated alginate chitosan nanoparticles, their anti-proliferative activity on C6 glioma cells. Carbohydrate Polymer Technologies and Applications, 2, 100106. https://doi.org/10.1016/j.carpta.2021.100106
Work Experience
The individual is involved in the comprehensive evaluation of phytochemicals for various bioactivities, employing a wide range of techniques and methodologies. The evaluation spans diverse fields including diabetology, cancer biology, inflammation, oxidative stress, toxicology, animal reproductive biology, antiviral activities, hepatoprotection, intestinal absorption, immunomodulation, plant-animal interaction, and targeted drug delivery using nano particles. The techniques employed include animal cell culture, Western blotting, gene expression studies, cell signaling studies, in vitro and in vivo evaluations of phytochemicals, short-term and long-term toxicity assessments, in vitro evaluation of anti-viral activity, next-generation sequencing (NGS) and transcriptome analysis, radioactive incorporation assays, various microscopic techniques, flow cytometry, electron microscopy, spectroscopy (FT-IR, UV-Vis, circular dichroism), plate readers, rheometer, and scintillation counter. This multi-faceted approach reflects a comprehensive investigation into the pharmacological potential and mechanisms of action of phytochemicals.